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February 1995

February 1995
Scientific American Magazine

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No, Really, It Was This Big; February 1995; Scientific American Magazine; by Vames; 1 Page(s)

Researchers at Fisheries and Oceans Canada in West Vancouver have engineered a fly-fisherman¿s fantasy. Robert H. Devlin and his colleagues altered the DNA of Pacific salmon to create fish that are, on average, more than 11 times bigger than their natural counterparts.

To spawn these gargantuan creatures, the group used the process that has stimulated similar growth in transgenic mice. The investigators microinjected growth promoter genes from two sources into the Pacific salmon eggs. The first source was a nonhomologous species--in this case, the mouse. The second, homologous source was sockeye salmon. The scientists then hatched the some 3,000 eggs and examined the offspring that survived to at least one year of age.



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