The Doping Dilemma; April 2008; Scientific American Magazine; by Michael Shermer; 8 Page(s)

For a competitive cyclist, there is nothing more physically crushing and psychologically demoralizing than getting dropped by your competitors on a climb. With searing lungs and burning legs, your body hunches over the handlebars as you struggle to stay with the leader. You know all too well that once you come off the back of the pack the drive to push harder is gone--and with it any hope for victory.

I know the feeling because it happened to me in 1985 on the long climb out of Albuquerque during the 3,000-mile, nonstop transcontinental Race Across America. On the outskirts of town I had caught up with the second-place rider (and eventual winner), Jonathan Boyer, a svelte road racer who was the first American to compete in the Tour de France. About halfway up the leg-breaking climb, that familiar wave of crushing fatigue swept through my legs as I gulped for oxygen in my struggle to hang on.